Simultaneous Determination of Chlorotetracycline and Benzocaine in Bolus by Chemometric Methods
نویسندگان
چکیده
ERDAL DINÇ1*, MURAT KANBUR2 , DUMITRU BALEANU3-4 Department of Analytical Chemistry, Faculty of Pharmacy, Ankara University, 06100, Tandoðan, Ankara, Turkey 2 Faculty of Veterinary Medicine, Department of Pharmacology and Toxicology, Kocasinan, Kayseri, Turkey 3 Department of Mathematics and Computer Sciences, Faculty of Arts and Sciences, Çankaya University, 06530 Balgat, Ankara, Turkey 4National Institute for Laser, Plasma and Radiation Physics, Institute of Space Sciences, Mãgurele-Bucharest, P.O. Box, MG-23,
منابع مشابه
Simultaneous Spectrophotometric Determination of Mycophenolate Mofetil and Its Active Metabolite in Human Plasma Using Chemometrics Methods
A spectrophotometric method for selective complexation reaction and simultaneous determination of mycophenolate mofetil (MPM), and mycophenolic acid (MPA) using three multivariate chemometric methods, i.e. partial least squares regression, principal component regression and principal component artificial neural networks, is proposed. The method is based on the complexation reaction of ...
متن کاملSimultaneous spectrophotometric determination of lidocaine and hydrocortisone acetate in pharmaceutical preparations by multivariate calibration methods
The multivariate calibration method, partial least square regression (PLS) was applied for thesimultaneous spectrophotometric determination of Lidocaine (LID) and Hydrocortisone acetate(HCA) in their mixtures. The parameters of chemometric technique were optimized and theproposed method was validated with synthetic samples and applied to analyze these drugs inpharmaceutical products with good a...
متن کاملSimultaneous spectrophotometric determination of Rifampicin, Isoniazid and Pyrazinamide in a single step
Three antituberculosis medications are investigated in this work consist of rifampicin, isoniazid and pyrazinamide. The ultra violet (UV) spectra of these compounds are overlapped, thus use of suitable chemometric methods are helpful for simultaneous spectrophotometric determination of them. A generalized version of net analyte signal standard addition method (GNASSAM) was used for determinatio...
متن کاملSimultaneous spectrophotometric determination of Rifampicin, Isoniazid and Pyrazinamide in a single step
Three antituberculosis medications are investigated in this work consist of rifampicin, isoniazid and pyrazinamide. The ultra violet (UV) spectra of these compounds are overlapped, thus use of suitable chemometric methods are helpful for simultaneous spectrophotometric determination of them. A generalized version of net analyte signal standard addition method (GNASSAM) was used for determinatio...
متن کاملEXTRACTION-SPECTROPHOTOMETRIC DETERMINATION OF BENZOCAINE BY DICYCLOHEXYL-18-CROWN-6 AND CALMAGITE
A simple and sensitive extraction-spectrophotometric method for rapid and accurate determination of benzocaine in pure and dosage forms was developed. Benzocaine was effectively extracted as a 1:1 ion pair complex with dicyclohexyl-18-crown-6 and calmagite in acidic media into chloroform, followed by spectrophotometric determination at 486 nm. Molar absorptivity of the ternary complex at this w...
متن کامل